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A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF

Advancing Bone Graft TechnologyA Surgeon’s Vision

As a practicing orthopedic surgeon, I have used fluorine to effectively treat osteoporosis patients, but its availability was banned by the Indian government due to concerns about overexposure. At the same time, I frequently encounter patients suffering from the devastating effects of chronic fluorosis, particularly those with cervical compressive myelopathy. This extreme contrast—fluorine’s immense therapeutic potential and its hazardous consequences—sparked my determination to explore a balanced approach. My focus has been on optimizing fluorine concentration in phosphate-based bioglass to leverage its bone anabolic properties while minimizing risks. This research has led to the development of a truly innovative bone graft substitute.”

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For Dr.S PugalanthiPandian, a dedicated Orthopedic and Neurosurgeon, the quest for better synthetic bone substitutes has been more than just a professional pursuit—it has been a lifelong passion driven by firsthand experience in treating patients with complex bone disorders.

With 40 years of experience in orthopedic surgery, Dr.Pandian has witnessed the dual nature of fluorine in bone health. On one hand, fluorine has shown remarkable potential in treating osteoporosis, aiding in bone regeneration and strengthening skeletal structures. On the other hand, chronic fluorosis—caused by excessive fluorine exposure—has led to severe complications such as cervical compressive myelopathy, a debilitating condition that often requires surgical intervention like laminoplasty.

This deep understanding of bone biology, surgical challenges, and material science has culminated in the creation of a next-generation synthetic bone graft—one that offers an optimal balance of safety, efficacy, and regenerative potential.
With this breakthrough, Dr.Pandian’s vision is to revolutionize the field of bone grafting, providing medical device manufacturers, biotech firms, and healthcare professionals with a superior alternative that enhances bone healing, integration, and long-term patient outcomes.

Advancing Bone Graft TechnologyPatent Offering

We are offering an exclusive opportunity to acquire our patented innovation, “A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF.”

This next-generation synthetic bone graft is designed to accelerate bone healing and integration, providing a superior alternative to conventional solutions.

This breakthrough technology is ideal for medical device manufacturers, biotech firms, and health care investors looking to stay ahead in the bone graft industry

Faster Bone Regeneration

Promotes high osteo-conversion within few weeks

Enhanced Compatibility

Offers osteoconductive, osteoinductive, and osteo-convertible properties

Versatile Forms

Available as granules, strips, and cylinders

A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF

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Granted

India

Granted

South Africa

Granted

China

Granted

Singapore

Granted

Australia

Novelty Accepted, Claims Modified

Saudi Arabia

Novelty Accepted, Claims Modified

Canada

Novelty Accepted, Claims Modified

European Union

Novelty Accepted, Claims Modified

UAE

In Progress

USA

In Progress

South Korea

Revolutionizing Wound Healing: A Breakthrough Ointment for Faster RecoveryPatent Offering

Throughout my 40 years of clinical practice, treating avascular wounds has remained a significant challenge. Burn wounds, bedsores, and diabetic ulcers require a superior solution—one that promotes rapid vascularization (VEGF), enhances fibroblast growth (FGF) for wound contraction, and accelerates epithelial regeneration (EGF) for closure.

Our patented ointment, formulated with Nano powder of Magnesium Fluoro Phosphate, has demonstrated remarkable efficacy. Lab studies confirm a multifold increase in VEGF, FGF, and EGF stimulation, while animal studies further validate its impact through histopathological, histochemical (VEGF), and immunochemical (Ki67) analyses—revealing comprehensive healing across all 17 key factors.

Now, it’s time to bring this breakthrough to human use, offering new hope to millions suffering from chronic wounds, diabetic ulcers, bedsores, and burn injuries. We are actively seeking manufacturing partners from the pharmaceutical industry to collaborate in bringing this revolutionary ointment to market. We are open to licensing our patented formulation to established pharma companies with expertise in wound care, ensuring that this innovation reaches those who need it most.

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Reach Us for Expert GuidanceConnect with us

If you are interested in acquiring or collaborating on this cutting-edge bone graft technology, Seize This Opportunity! Let’s connect!

Contact us to explore acquisition and partnership possibilities.

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Where Innovation Meets Bone SciencePublications

Published
3 March 2021

Preparation and Physico-Chemical Characterization Studies of Fluoride Doped Bioceramics (P2O5-CaO-CaF2-Na2O) for Bone Regeneration
Bioceramics Developments and Applications

Published
2024

Magnesium-doped Fluorophosphate Bioactive Glass for Bone Tissue Engineering: in vitro and in vivo study

SI NO. PATENT NATIONALITY STATUS
1. A FORMULATION FOR WOUND HEALING
India
Granted
2. A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF
India
Granted
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF South Africa Granted
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF Singapore Granted
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF Australia Granted
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF China Granted
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF UAE Novelty Accepted, Claims Modified
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF Saudi Arabia Novelty Accepted, Claims Modified
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF Canada Novelty Accepted, Claims Modified
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF European Union Novelty Accepted, Claims Modified
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF South Korea In Progress
A SYNTHETIC COMPOSITE AS BONE GRAFT AND THE METHOD THEREOF USA In Progress
3. SILVER ADDED FLUOROPHOSPHATE GLASSES AND METHOD OF MAKING THEREOF India Granted
4. BIOCONVERSION OF ZINC ADDED FLUOROPHOSPHATE GLASSES AND METHOD OF MAKING THEREOF India Granted
5. BIOACTIVITY OF FLUOROPHOSPHATE GLASSES AND METHOD OF MAKING THEREOF India Granted
6. BIOCONVERSTION OF MAGNESIUM ADDED FLOROPHOSPHATE GLASSES AND METHOD OF MAKING THEREOF India Granted
7. BIOCONVERSION OF TITANIUM ADDED FLUOROPHOSPHATE CLASSES AND METHOD OF MAKING THEREOF India Granted, Ceased
8. BIOCONVERSION OF ZIRCONIUM ADDED FLUOROPHOSPHATE GLASSES AND METHOD OF MAKING THEREOF India Granted, Ceased
9. BIOCONVERSION OF STRONTIUM ADDED FLUOROPHOSPHATE GLASSES AND METHOD OF MAKING THEREOF India Granted, Ceased